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Listar por autor "Carmona Cuenca, Irene"
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Artículo
Age-dependent accumulation of soluble amyloid β (Aβ) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-α (sAPPα) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK- 3β pathway in Alzheimer mouse model
Jiménez Muñoz, Sebastián; Torres Canalejo, Manuel; Vizuete Chacón, María Luisa; Sánchez Varo, Raquel María; Sánchez Mejías, Elisabeth; Trujillo Estrada, Laura Isabel; Carmona Cuenca, Irene; Caballero, Cristina M.; Ruano Caballero, Diego; Gutiérrez Pérez, Antonia; Vitorica Ferrández, Francisco Javier (American Society for Biochemistry and Molecular Biology Inc., 2011)Neurotrophins, activating the PI3K/Akt signaling pathway, control neuronal survival and plasticity. Alterations in NGF, ...
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Artículo
Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus
Gutiérrez Pérez, Antonia; Vitorica Ferrández, Francisco Javier; Dávila Cansino, José Carlos; Vizuete Chacón, María Luisa; Carmona Cuenca, Irene; Jiménez Muñoz, Sebastián; Trujillo Estrada, Laura Isabel; Sánchez Varo, Raquel María; Torres Canalejo, Manuel; Sánchez Mejías, Elisabeth; Navarro Garrido, Victoria (2012)Background: Axonal pathology might constitute one of the earliest manifestations of Alzheimer disease. Axonal dystrophies ...